2PPZ

NMR solution Structure of the Villin Headpiece Mutant G34L

2PPZ の概要

• エントリーDOI: 10.2210/pdb2ppz/pdb
• NMR情報: BMRB: 15245
• 分子名称: Villin-1 (1 entity in total)
• 機能のキーワード: small stable core, alpha helical, thermostable, in silico sequence optimization, structural protein
• 由来する生物種: Gallus gallus (chicken)
• 細胞内の位置: Cytoplasm, cytoskeleton: P02640
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4252.01

構造登録者

Gronwald, W.,Hohm, T.,Hoffmann, D. (登録日: 2007-05-01, 公開日: 2007-05-29, 最終更新日: 2024-05-22)

主引用文献

Gronwald, W.,Hohm, T.,Hoffmann, D.
Evolutionary Pareto-optimization of stably folding peptides
Bmc Bioinformatics, 9:109-109, 2008

PubMed Abstract: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides have been discovered. This raises the question whether there may be more such peptides that are unknown as yet. These molecules could be helpful in basic research and medicine.

PubMed: 18284690
DOI: 10.1186/1471-2105-9-109

実験手法

SOLUTION NMR