2PON
Solution structure of the Bcl-xL/Beclin-1 complex
Summary for 2PON
Entry DOI | 10.2210/pdb2pon/pdb |
Descriptor | Beclin-1, Apoptosis regulator Bcl-X (2 entities in total) |
Functional Keywords | apoptosis; autophagy; bcl-2 family proteins; beclin-1, apoptosis inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein: Q14457 Mitochondrion membrane; Single-pass membrane protein (By similarity): Q07817 |
Total number of polymer chains | 2 |
Total formula weight | 20398.60 |
Authors | |
Primary citation | Feng, W.,Huang, S.,Wu, H.,Zhang, M. Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1. J.Mol.Biol., 372:223-235, 2007 Cited by PubMed: 17659302DOI: 10.1016/j.jmb.2007.06.069 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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