2POA

Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue

2POA の概要

• エントリーDOI: 10.2210/pdb2poa/pdb
• NMR情報: BMRB: 6150
• 分子名称: 14 kDa fatty acid-binding protein (1 entity in total)
• 機能のキーワード: schistosoma mansoni, fatty acid binding protein, site directed mutagenesis, protein stability, molecular dynamics, vaccine antigen, lipid binding protein
• 由来する生物種: Schistosoma mansoni (Blood fluke)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14862.77

構造登録者

Ramos, C.R.R.,Oyama Jr., S.,Sforca, M.L.,Pertinhez, T.A.,Ho, P.L.,Spisni, A. (登録日: 2007-04-26, 公開日: 2008-06-10, 最終更新日: 2024-05-15)

• 主引用文献: Ramos, C.R.,Spisni, A.,Oyama, S.,Sforca, M.L.,Ramos, H.R.,Vilar, M.M.,Alves, A.C.,Figueredo, R.C.,Tendler, M.,Zanchin, N.I.,Pertinhez, T.A.,Ho, P.L.; Stability improvement of the fatty acid binding protein Sm14 from S. mansoni by Cys replacement: Structural and functional characterization of a vaccine candidate.; Biochim.Biophys.Acta, 1794:655-662, 2009; PubMed: 19150418; DOI: 10.1016/j.bbapap.2008.12.010

実験手法

SOLUTION NMR