2PO3

Crystal Structure Analysis of DesI in the presence of its TDP-sugar product

2PO3 の概要

• エントリーDOI: 10.2210/pdb2po3/pdb
• 分子名称: 4-dehydrase, (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE (3 entities in total)
• 機能のキーワード: external aldimine, plp, aminotransferase, tdp-sugar, transferase
• 由来する生物種: Streptomyces venezuelae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92513.14

構造登録者

Burgie, E.S.,Holden, H.M. (登録日: 2007-04-25, 公開日: 2007-08-14, 最終更新日: 2023-08-30)

• 主引用文献: Burgie, E.S.,Holden, H.M.; Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine; Biochemistry, 46:8999-9006, 2007; PubMed: 17630700; DOI: 10.1021/bi700751d

実験手法

X-RAY DIFFRACTION (2.1 Å)