2PMS

Crystal structure of the complex of human lactoferrin N-lobe and lactoferrin-binding domain of pneumococcal surface protein A

Summary for 2PMS

• Entry DOI: 10.2210/pdb2pms/pdb
• Related: 1EH3 1H43 1H44 1H45 1LCT
• Descriptor: Lactotransferrin, PNEUMOCOCCAL SURFACE PROTEIN A (PSPA), 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: lactoferrin, pneumococcal surface protein a, protein-protein complex, metal transport, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 106181.33

Authors

Chattopadhyay, D.,Senkovich, O.,Cook, W.J. (deposition date: 2007-04-23, release date: 2007-06-19, Last modification date: 2023-08-30)

• Primary citation: Senkovich, O.,Cook, W.J.,Mirza, S.,Hollingshead, S.K.,Protasevich, I.I.,Briles, D.E.,Chattopadhyay, D.; Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.; J.Mol.Biol., 370:701-713, 2007; PubMed: 17543335; DOI: 10.1016/j.jmb.2007.04.075

Experimental method

X-RAY DIFFRACTION (2.91 Å)