2PML

Crystal structure of PfPK7 in complex with an ATP analogue

Summary for 2PML

• Entry DOI: 10.2210/pdb2pml/pdb
• Descriptor: Ser/Thr protein kinase, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: ser/thr protein kinase; plasmodium falciparum; phosphorylation; transferase, transferase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 1
• Total formula weight: 41995.73

Authors

Merckx, A.,Echalier, A.,Noble, M.,Endicott, J. (deposition date: 2007-04-23, release date: 2008-01-22, Last modification date: 2024-02-21)

• Primary citation: Merckx, A.,Echalier, A.,Langford, K.,Sicard, A.,Langsley, G.,Joore, J.,Doerig, C.,Noble, M.,Endicott, J.; Structures of PfPK7 an atypical protein kinase from P. falciparum identify a novel activation motif and leads for inhibitor design; To be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)