2PIK

CALICHEAMICIN GAMMA1I-DNA COMPLEX, NMR, 6 STRUCTURES

Summary for 2PIK

• Entry DOI: 10.2210/pdb2pik/pdb
• Descriptor: DNA(5'-D(C*AP*CP*TP*CP*CP*TP*GP*GP*TP*TP*TP*TP* TP*GP*TP*GP*AP*GP*GP*AP*CP*CP)-3'), 2,4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-thio-beta-D-allopyranose, ... (6 entities in total)
• Functional Keywords: deoxyribonucleic acid, calicheamicin gamma1i - dna complex, enediyne alignment in minor groove, saccharide dna minor groove interactions, intermolecular drug iodine-guanine amino proton interactions, specificity and cleavage process, dna
• Total number of polymer chains: 1
• Total formula weight: 8446.94

Authors

Kumar, R.A.,Ikemoto, N.,Patel, D.J. (deposition date: 1996-12-31, release date: 1997-05-15, Last modification date: 2020-07-29)

• Primary citation: Kumar, R.A.,Ikemoto, N.,Patel, D.J.; Solution structure of the calicheamicin gamma 1I-DNA complex.; J.Mol.Biol., 265:187-201, 1997; PubMed: 9020982; DOI: 10.1006/jmbi.1996.0718

Experimental method

SOLUTION NMR