2PH9

Galanthamine bound to an ACh-binding Protein

2PH9 の概要

• エントリーDOI: 10.2210/pdb2ph9/pdb
• 関連するPDBエントリー: 2PGZ
• 分子名称: Soluble acetylcholine receptor, (-)-GALANTHAMINE, TETRAETHYLENE GLYCOL, ... (4 entities in total)
• 機能のキーワード: non-competitive inhibitors, nicotinic acetylcholine receptor, acetylcholine-binding protein, benzodiazepine, galanthamine, choline-binding protein
• 由来する生物種: Aplysia californica (California sea hare)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 132404.17

構造登録者

Hansen, S.B.,Taylor, P. (登録日: 2007-04-10, 公開日: 2007-07-03, 最終更新日: 2023-08-30)

• 主引用文献: Hansen, S.B.,Taylor, P.; Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.; J.Mol.Biol., 369:895-901, 2007; PubMed: 17481657; DOI: 10.1016/j.jmb.2007.03.067

実験手法

X-RAY DIFFRACTION (2.88 Å)