2PEY

Crystal structure of deletion mutant of APS-kinase domain of human PAPS-synthetase 1

2PEY の概要

• エントリーDOI: 10.2210/pdb2pey/pdb
• 関連するPDBエントリー: 2pez
• 分子名称: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1), ADENOSINE-5'-PHOSPHOSULFATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: protein-nucleic acid complex, nmp-kinase fold, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 40998.63

構造登録者

Sekulic, N.,Lavie, A. (登録日: 2007-04-03, 公開日: 2007-05-29, 最終更新日: 2023-08-30)

• 主引用文献: Sekulic, N.,Konrad, M.,Lavie, A.; Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation.; J.Biol.Chem., 282:22112-22121, 2007; PubMed: 17540769; DOI: 10.1074/jbc.M701713200

実験手法

X-RAY DIFFRACTION (1.88 Å)