2PED

Crystallographic model of 9-cis-rhodopsin

2PED の概要

• エントリーDOI: 10.2210/pdb2ped/pdb
• 関連するPDBエントリー: 1U19 2G87
• 分子名称: Rhodopsin, HEPTANE-1,2,3-TRIOL, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: rhodopsin, g protein-coupled receptor, visual pigment, signaling protein
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Membrane; Multi-pass membrane protein: P02699
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85393.66

構造登録者

Nakamichi, H.,Okada, T. (登録日: 2007-04-02, 公開日: 2007-10-30, 最終更新日: 2024-10-30)

主引用文献

Nakamichi, H.,Buss, V.,Okada, T.
Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography
Biophys.J., 92:L106-L108, 2007

PubMed Abstract: The primary photochemical process of the visual function has been investigated using the three crystallographic models, 11-cis-rhodopsin, all-trans-bathorhodopsin, and the artificial isomeric 9-cis-rhodopsin. Detailed examination of the atomic displacements and dihedral angle changes of the retinal chromophore involved in the interconversion among these isomers suggests the mechanism of isomerization efficiency.

PubMed: 17449675
DOI: 10.1529/biophysj.107.108225

実験手法

X-RAY DIFFRACTION (2.95 Å)