2PE5

Crystal Structure of the Lac Repressor bound to ONPG in repressed state

Summary for 2PE5

• Entry DOI: 10.2210/pdb2pe5/pdb
• Related: 2P9H 2PAF
• Descriptor: DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor, 2-nitrophenyl beta-D-galactopyranoside (3 entities in total)
• Functional Keywords: lac repressor, allosteric effectors, gene regulation, dna-binding, transcription, transcription regulation, transcription-dna complex, transcription/dna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 6
• Total formula weight: 125534.03

Authors

Daber, R.,Stayrook, S.E.,Rosenberg, A.,Lewis, M. (deposition date: 2007-04-02, release date: 2008-03-18, Last modification date: 2023-08-30)

• Primary citation: Daber, R.,Stayrook, S.,Rosenberg, A.,Lewis, M.; Structural analysis of lac repressor bound to allosteric effectors; J.Mol.Biol., 370:609-619, 2007; PubMed: 17543986; DOI: 10.1016/j.jmb.2007.04.028

Experimental method

X-RAY DIFFRACTION (3.5 Å)