2PBJ
GSH-heme bound microsomal prostaglandin E synthase
Summary for 2PBJ
| Entry DOI | 10.2210/pdb2pbj/pdb |
| Descriptor | Prostaglandin E synthase 2, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
| Functional Keywords | prostaglandin e synthase, gsh-heme bound enzyme, dual function enzyme, isomerase, lyase |
| Biological source | Macaca fascicularis (crab-eating macaque) |
| Cellular location | Golgi apparatus membrane; Single-pass membrane protein (By similarity). Prostaglandin E synthase 2 truncated form: Cytoplasm, perinuclear region (By similarity): Q9N0A4 |
| Total number of polymer chains | 4 |
| Total formula weight | 136436.29 |
| Authors | Takusagawa, F.,Yamada, T. (deposition date: 2007-03-28, release date: 2008-02-12, Last modification date: 2024-02-21) |
| Primary citation | Yamada, T.,Takusagawa, F. PGH2 degradation pathway catalyzed by GSH-heme complex bound microsomal prostaglandin E2 synthase type 2: the first example of a dual-function enzyme. Biochemistry, 46:8414-8424, 2007 Cited by PubMed: 17585783DOI: 10.1021/bi700605m PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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