2P4L

Structure and sodium channel activity of an excitatory I1-superfamily conotoxin

2P4L の概要

• エントリーDOI: 10.2210/pdb2p4l/pdb
• NMR情報: BMRB: 15174
• 分子名称: I-superfamily conotoxin r11a (1 entity in total)
• 機能のキーワード: iaa, iodoacetic acid; ina, sodium current; nem, n-ethylmaleimide; nmr, nuclear magnetic resonance; noe, nuclear overhauser effect; tfa, trifluoroacetic acid; vgsc, voltage-gated sodium channel., toxin
• 由来する生物種: Conus radiatus
• 細胞内の位置: Secreted: Q7Z094
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4987.67

構造登録者

Buczek, O.,Wei, D.X.,Babon, J.J.,Yang, X.D.,Fiedler, B.,Yoshikami, D.,Olivera, B.M.,Bulaj, G.,Norton, R.S. (登録日: 2007-03-12, 公開日: 2007-09-25, 最終更新日: 2022-03-16)

• 主引用文献: Buczek, O.,Wei, D.,Babon, J.J.,Yang, X.,Fiedler, B.,Chen, P.,Yoshikami, D.,Olivera, B.M.,Bulaj, G.,Norton, R.S.; Structure and Sodium Channel Activity of an Excitatory I(1)-Superfamily Conotoxin; Biochemistry, 46:9929-9940, 2007; PubMed: 17696362; DOI: 10.1021/bi700797f

実験手法

SOLUTION NMR