2P39

Crystal structure of human FGF23

Summary for 2P39

• Entry DOI: 10.2210/pdb2p39/pdb
• Related: 2P23
• Related PRD ID: PRD_900013
• Descriptor: Fibroblast growth factor 23, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: atypical beta-trefoil fold, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 18839.04

Authors

Mohammadi, M. (deposition date: 2007-03-08, release date: 2007-04-10, Last modification date: 2023-08-30)

• Primary citation: Goetz, R.,Beenken, A.,Ibrahimi, O.A.,Kalinina, J.,Olsen, S.K.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Zhang, F.,Linhardt, R.J.,Yu, X.,White, K.E.,Inagaki, T.,Kliewer, S.A.,Yamamoto, M.,Kurosu, H.,Ogawa, Y.,Kuro-O, M.,Lanske, B.,Razzaque, M.S.,Mohammadi, M.; Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.; Mol.Cell.Biol., 27:3417-3428, 2007; PubMed: 17339340; DOI: 10.1128/MCB.02249-06

Experimental method

X-RAY DIFFRACTION (1.5 Å)