2P2T

Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74

Summary for 2P2T

Entry DOI	10.2210/pdb2p2t/pdb
Related	2P1K
Descriptor	Dynein light chain 1, cytoplasmic, Dynein intermediate chain peptide, ACETATE ION, ... (5 entities in total)
Functional Keywords	protein - peptide complex, transport protein
Biological source	Drosophila melanogaster (fruit fly) More
Cellular location	Cytoplasm, cytoskeleton : Q24117 Cytoplasm, cytoskeleton . Isoform 2c: Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Isoform 2a: Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Isoform 2b: Nucleus membrane; Peripheral membrane protein; Cytoplasmic side: Q24246
Total number of polymer chains	2
Total formula weight	12258.84
Authors	Benison, G.,Karplus, P.A.,Barbar, E. (deposition date: 2007-03-07, release date: 2008-01-15, Last modification date: 2024-02-21)
Primary citation	Benison, G.,Karplus, P.A.,Barbar, E. Structure and dynamics of LC8 complexes with KXTQT-motif peptides: swallow and dynein intermediate chain compete for a common site. J.Mol.Biol., 371:457-468, 2007 Cited by PubMed: 17570393 DOI: 10.1016/j.jmb.2007.05.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation