2P1D

Crystal structure of dengue methyltransferase in complex with GTP and S-Adenosyl-L-homocysteine

Summary for 2P1D

• Entry DOI: 10.2210/pdb2p1d/pdb
• Related: 1L9K
• Descriptor: type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: vizier; viral enzymes involved in replication; dengue virus methyltransferase; structural genomics; marseilles structural genomics program @ afmb; msgp, vizier. viral enzymes involved in replication, viral protein, transferase
• Biological source: Dengue virus 2
• Cellular location: Envelope protein E: Virion membrane; Multi- pass membrane protein: Q9WLZ8
• Total number of polymer chains: 1
• Total formula weight: 36105.29

Authors

Egloff, M.P.,Benarooch, D.,Marseilles Structural Genomics Program @ AFMB (MSGP) (deposition date: 2007-03-05, release date: 2007-03-20, Last modification date: 2023-08-30)

• Primary citation: Egloff, M.P.,Benarroch, D.,Selisko, B.,Romette, J.L.,Canard, B.; An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization; EMBO J., 21:2757-2768, 2002; PubMed: 12032088; DOI: 10.1093/emboj/21.11.2757

Experimental method

X-RAY DIFFRACTION (2.9 Å)