2OZK
Structure of an N-Terminal Truncated Form of Nendou (NSP15) From SARS-CORONAVIRUS
Summary for 2OZK
Entry DOI | 10.2210/pdb2ozk/pdb |
Descriptor | Uridylate-specific endoribonuclease (1 entity in total) |
Functional Keywords | endonuclease nendou, ribonuclease, homolog of xenopus xendou, sars nsp15, n-terminal truncated construct, viral protein |
Biological source | SARS coronavirus |
Cellular location | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
Total number of polymer chains | 4 |
Total formula weight | 154131.19 |
Authors | Saikatendu, K.,Joseph, J.,Subramanian, V.,Neuman, B.,Buchmeier, M.,Stevens, R.C.,Kuhn, P. (deposition date: 2007-02-26, release date: 2007-05-29, Last modification date: 2023-08-30) |
Primary citation | Joseph, J.S.,Saikatendu, K.S.,Subramanian, V.,Neuman, B.W.,Buchmeier, M.J.,Stevens, R.C.,Kuhn, P. Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch. J.Virol., 81:6700-6708, 2007 Cited by PubMed: 17409150DOI: 10.1128/JVI.02817-06 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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