2OVM

Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor NCoR

2OVM の概要

• エントリーDOI: 10.2210/pdb2ovm/pdb
• 関連するPDBエントリー: 1A28 2OVH
• 分子名称: Progesterone receptor, NCoR, 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, ... (4 entities in total)
• 機能のキーワード: progesterone receptor, pr, nuclear receptor, steroid receptor, co-repressor, asoprisnil, ncor, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32654.21

構造登録者

Madauss, K.P.,Deng, S.-J.,Short, S.A.,Stewart, E.L.,Williams, S.P. (登録日: 2007-02-14, 公開日: 2007-03-20, 最終更新日: 2023-08-30)

• 主引用文献: Madauss, K.P.,Grygielko, E.T.,Deng, S.J.,Sulpizio, A.C.,Stanley, T.B.,Wu, C.,Short, S.A.,Thompson, S.K.,Stewart, E.L.,Laping, N.J.,Williams, S.P.,Bray, J.D.; A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator.; Mol.Endocrinol., 21:1066-1081, 2007; PubMed: 17356170; DOI: 10.1210/me.2006-0524

実験手法

X-RAY DIFFRACTION (2.6 Å)