2OVH
Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor SMRT
Summary for 2OVH
Entry DOI | 10.2210/pdb2ovh/pdb |
Related | 1A28 2OVM |
Descriptor | Progesterone receptor, SMRT peptide, 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, ... (4 entities in total) |
Functional Keywords | progesterone receptor, pr, nuclear receptor, steroid receptor, co-repressor, asoprisnil, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus. Isoform A: Nucleus. Isoform 4: Mitochondrion outer membrane : P06401 |
Total number of polymer chains | 2 |
Total formula weight | 31916.56 |
Authors | Madauss, K.P.,Deng, S.-J.,Short, S.A.,Stewart, E.L.,Williams, S.P. (deposition date: 2007-02-13, release date: 2007-03-20, Last modification date: 2024-03-13) |
Primary citation | Madauss, K.P.,Grygielko, E.T.,Deng, S.J.,Sulpizio, A.C.,Stanley, T.B.,Wu, C.,Short, S.A.,Thompson, S.K.,Stewart, E.L.,Laping, N.J.,Williams, S.P.,Bray, J.D. A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator. Mol.Endocrinol., 21:1066-1081, 2007 Cited by PubMed: 17356170DOI: 10.1210/me.2006-0524 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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