2OTX
Crystal Structure of A N-terminal Fragment of SKAP-HOM Containing both the Helical Dimerization Domain and the PH Domain
Summary for 2OTX
Entry DOI | 10.2210/pdb2otx/pdb |
Related | 1U5D 1U5F 1U5G |
Descriptor | Src kinase-associated phosphoprotein 2 (2 entities in total) |
Functional Keywords | novel dimerization domain, ph domain, signaling protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm: Q3UND0 |
Total number of polymer chains | 2 |
Total formula weight | 48343.96 |
Authors | Tang, Y.,Swanson, K.D.,Neel, B.G.,Eck, M.J. (deposition date: 2007-02-09, release date: 2007-03-27, Last modification date: 2023-08-30) |
Primary citation | Swanson, K.D.,Tang, Y.,Ceccarelli, D.F.,Poy, F.,Sliwa, J.P.,Neel, B.G.,Eck, M.J. The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch. Mol.Cell, 32:564-575, 2008 Cited by PubMed: 19026786DOI: 10.1016/j.molcel.2008.09.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report