2OSG

Solution Structure and Binding Property of the Domain-swapped Dimer of ZO2PDZ2

Summary for 2OSG

• Entry DOI: 10.2210/pdb2osg/pdb
• Descriptor: Tight junction protein ZO-2 (1 entity in total)
• Functional Keywords: tight junction, zo-2, pdz domain, homodimer, domain swapping, cell adhesion
• Biological source: Homo sapiens (human)
• Cellular location: Cell junction, adherens junction: Q9UDY2
• Total number of polymer chains: 2
• Total formula weight: 18545.68

Authors

Wu, J.W.,Yang, Y.S.,Zhang, J.H.,Ji, P.,Wu, J.H.,Shi, Y.Y. (deposition date: 2007-02-05, release date: 2007-09-25, Last modification date: 2022-03-16)

• Primary citation: Wu, J.W.,Yang, Y.S.,Zhang, J.H.,Ji, P.,Du, W.J.,Jiang, P.,Xie, D.H.,Huang, H.D.,Wu, M.,Zhang, G.Z.,Wu, J.H.,Shi, Y.Y.; Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins; J.Biol.Chem., 282:35988-35999, 2007; PubMed: 17897942; DOI: 10.1074/jbc.M703826200

Experimental method

SOLUTION NMR