2OR9

The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops

Summary for 2OR9

• Entry DOI: 10.2210/pdb2or9/pdb
• Related: 2ORB
• Descriptor: Monoclonal anti-c-myc antibody 9E10, synthetic epitope peptide of 9E10, ... (4 entities in total)
• Functional Keywords: antigen-antibody complex, antigen recognition, myc-tag, long cdr h3, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 5
• Total formula weight: 99121.09

Authors

Krauss, N.,Scheerer, P.,Hoehne, W. (deposition date: 2007-02-02, release date: 2008-02-12, Last modification date: 2023-08-30)

• Primary citation: Krauss, N.,Wessner, H.,Welfle, K.,Welfle, H.,Scholz, C.,Seifert, M.,Zubow, K.,Ay, J.,Hahn, M.,Scheerer, P.,Skerra, A.,Hohne, W.; The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops.; Proteins, 73:552-565, 2008; PubMed: 18473392; DOI: 10.1002/prot.22080

Experimental method

X-RAY DIFFRACTION (2.7 Å)