2OQ5

Crystal structure of DESC1, a new member of the type II transmembrane serine proteinases family

Summary for 2OQ5

Entry DOI	10.2210/pdb2oq5/pdb
Descriptor	Transmembrane protease, serine 11E, BENZAMIDINE (3 entities in total)
Functional Keywords	type ii trans-membrane serine proteinases, trypsin-like serine protease, tumor marker, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Single-pass type II membrane protein . Transmembrane protease serine 11E catalytic chain: Secreted : Q9UL52
Total number of polymer chains	1
Total formula weight	25643.83
Authors	Kyrieleis, O.J.P.,Huber, R.,Madison, E.L.,Jacob, U. (deposition date: 2007-01-31, release date: 2007-04-10, Last modification date: 2024-04-03)
Primary citation	Kyrieleis, O.J.P.,Huber, R.,Ong, E.,Oehler, R.,Hunter, M.,Madison, E.L.,Jacob, U. Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family. Febs J., 274:2148-2160, 2007 Cited by PubMed: 17388811 DOI: 10.1111/j.1742-4658.2007.05756.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.61 Å)

Structure validation