Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2OOZ

Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group)

Summary for 2OOZ
Entry DOI10.2210/pdb2ooz/pdb
Related2OOH 2OOW
DescriptorMacrophage migration inhibitory factor, SULFATE ION, 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME, ... (6 entities in total)
Functional Keywordsalternative ligand-binding modes, isomerase
Biological sourceHomo sapiens (human)
Cellular locationSecreted : P14174
Total number of polymer chains3
Total formula weight38352.42
Authors
Crichlow, G.V.,Al-Abed, Y.,Lolis, E. (deposition date: 2007-01-26, release date: 2007-06-05, Last modification date: 2023-08-30)
Primary citationCrichlow, G.V.,Cheng, K.F.,Dabideen, D.,Ochani, M.,Aljabari, B.,Pavlov, V.A.,Miller, E.J.,Lolis, E.,Al-Abed, Y.
Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282:23089-23095, 2007
Cited by
PubMed: 17526494
DOI: 10.1074/jbc.M701825200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon