2OO1

Crystal structure of the Bromo domain 2 of human Bromodomain containing protein 3 (BRD3)

2OO1 の概要

• エントリーDOI: 10.2210/pdb2oo1/pdb
• 分子名称: Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: brd3, bromodomain containing protein 3, orfx, ring3 like gene, ring3l, structural genomics, structural genomics consortium, sgc, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : Q15059
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 54144.57

構造登録者

Filippakopoulos, P.,Bullock, A.,Papagrigoriou, E.,Keates, T.,Cooper, C.,Smee, C.,Ugochukwu, E.,Debreczeni, J.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2007-01-25, 公開日: 2007-02-13, 最終更新日: 2023-08-30)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (1.7 Å)