2ON9

Structure of an amyloid forming peptide VQIVYK from the repeat region of Tau

2ON9 の概要

• エントリーDOI: 10.2210/pdb2on9/pdb
• 分子名称: VQIVYK peptide corresponding to residues 306-311 in the tau protein (2 entities in total)
• 機能のキーワード: parallel face-to-face-up/up beta sheets, steric zipper, protein fibril
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 1499.83

構造登録者

Sambashivan, S.,Sawaya, M.R.,Eisenberg, D. (登録日: 2007-01-23, 公開日: 2007-01-30, 最終更新日: 2024-04-03)

• 主引用文献: Sawaya, M.R.,Sambashivan, S.,Nelson, R.,Ivanova, M.I.,Sievers, S.A.,Apostol, M.I.,Thompson, M.J.,Balbirnie, M.,Wiltzius, J.J.,McFarlane, H.T.,Madsen, A.O.,Riekel, C.,Eisenberg, D.; Atomic structures of amyloid cross-beta spines reveal varied steric zippers.; Nature, 447:453-457, 2007; PubMed: 17468747; DOI: 10.1038/nature05695

実験手法

X-RAY DIFFRACTION (1.51 Å)