Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA

Summary for 2OJE

DescriptorHLA class II histocompatibility antigen, DR alpha chain precursor, HLA class II histocompatibility antigen, DRB1-1 beta chain precursor, haemagglutinin peptide 306-318, ... (6 entities in total)
Functional Keywordssuperantigen, mhc, immune system
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein P01903 P04229
Total number of polymer chains8
Total molecular weight140618.34
Li, H.,Zhao, Y.,Guo, Y.,Li, Z.,Eisele, L.,Mourad, W. (deposition date: 2007-01-12, release date: 2007-01-23, Last modification date: 2011-07-13)
Primary citation
Li, H.,Zhao, Y.,Guo, Y.,Li, Z.,Eisele, L.,Mourad, W.
Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.
J.Biol.Chem., 282:5991-6000, 2007
PubMed: 17166841 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M608482200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258220.8%6.7%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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