2ODB

The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)

2ODB の概要

• エントリーDOI: 10.2210/pdb2odb/pdb
• 関連するPDBエントリー: 1GRN
• 分子名称: Human Cell Division Cycle 42 (CDC42), Serine/threonine-protein kinase PAK 6, CHLORIDE ION, ... (7 entities in total)
• 機能のキーワード: small gtpase, crib, kinase, protein-protein complex, structural genomics, structural genomics consortium, sgc, protein binding
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q9NQU5; Cell membrane ; Lipid-anchor ; Cytoplasmic side : P60953
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26306.32

構造登録者

Ugochukwu, E.,Yang, X.,Elkins, J.,Soundararajan, M.,Pike, A.C.W.,Eswaran, J.,Burgess, N.,Debreczeni, J.E.,Sundstrom, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Gileadi, O.,von Delft, F.,Knapp, S.,Doyle, D.,Structural Genomics Consortium (SGC) (登録日: 2006-12-22, 公開日: 2007-01-30, 最終更新日: 2023-08-30)

• 主引用文献: Yang, X.,Ugochukwu, E.,Elkins, J.,Soundararajan, M.,Eswaran, J.,Pike, A.C.W.,Burgess, N.,Debreczeni, J.E.,Gileadi, O.,Knapp, S.,Doyle, D.; The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6); To be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)