2OBI
Crystal structure of the Selenocysteine to Cysteine Mutant of human phospholipid hydroperoxide glutathione peroxidase (GPx4)
Summary for 2OBI
| Entry DOI | 10.2210/pdb2obi/pdb |
| Descriptor | Phospholipid hydroperoxide glutathione peroxidase (GPX4) (2 entities in total) |
| Functional Keywords | human gpx4, peroxidase, selenoprotein, thioredoxin-fold, anti-oxidatve defense system, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Cellular location | Mitochondrion: P36969 |
| Total number of polymer chains | 1 |
| Total formula weight | 20955.08 |
| Authors | Scheerer, P.,Krauss, N.,Hoehne, W. (deposition date: 2006-12-19, release date: 2007-09-18, Last modification date: 2023-08-30) |
| Primary citation | Scheerer, P.,Borchert, A.,Krauss, N.,Wessner, H.,Gerth, C.,Hohne, W.,Kuhn, H. Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4). Biochemistry, 46:9041-9049, 2007 Cited by PubMed: 17630701DOI: 10.1021/bi700840d PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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