2O88
Crystal structure of the N114A mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
Summary for 2O88
Entry DOI | 10.2210/pdb2o88/pdb |
Related | 1BBZ |
Descriptor | Proto-oncogene tyrosine-protein kinase ABL1, P41 peptide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | sh3 domain high affinity peptide complex, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 4 |
Total formula weight | 15022.53 |
Authors | Camara-Artigas, A. (deposition date: 2006-12-12, release date: 2007-05-01, Last modification date: 2023-08-30) |
Primary citation | Camara-Artigas, A.,Palencia, A.,Martinez, J.C.,Luque, I.,Gavira, J.A.,Garcia-Ruiz, J.M. Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand. Acta Crystallogr.,Sect.D, 63:646-652, 2007 Cited by PubMed: 17452790DOI: 10.1107/S0907444907011109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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