2O74

Structure of OHCU decarboxylase in complex with guanine

Summary for 2O74

• Entry DOI: 10.2210/pdb2o74/pdb
• Related: 2O70 2O73
• Descriptor: OHCU decarboxylase, GUANINE (3 entities in total)
• Functional Keywords: decarboxylation, ohcu, 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline, hiu, 5-hydroxyisourate, lyase
• Biological source: Danio rerio (zebrafish)
• Cellular location: Peroxisome (Probable): A1L259
• Total number of polymer chains: 6
• Total formula weight: 119518.63

Authors

Cendron, L.,Berni, R.,Folli, C.,Ramazzina, I.,Percudani, R.,Zanotti, G. (deposition date: 2006-12-10, release date: 2007-04-10, Last modification date: 2023-10-25)

• Primary citation: Cendron, L.,Berni, R.,Folli, C.,Ramazzina, I.,Percudani, R.,Zanotti, G.; The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.; J.Biol.Chem., 282:18182-18189, 2007; PubMed: 17428786; DOI: 10.1074/jbc.M701297200

Experimental method

X-RAY DIFFRACTION (1.8 Å)