Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2O53

Crystal structure of apo-Aspartoacylase from human brain

Summary for 2O53
Entry DOI10.2210/pdb2o53/pdb
Related2O4H
DescriptorAspartoacylase, ZINC ION, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordscanavan disease, n-acetyl-l-aspartate, zinc-dependent hydrolase, aspartoacylase family, aminoacylase-2, acy2, aspa, n-phosphonomethyl-l-aspartate, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P45381
Total number of polymer chains2
Total formula weight72078.87
Authors
Le Coq, J.,Pavlovsky, A.,Sanishvili, R.,Viola, R.E. (deposition date: 2006-12-05, release date: 2007-11-06, Last modification date: 2023-08-30)
Primary citationLe Coq, J.,Pavlovsky, A.,Malik, R.,Sanishvili, R.,Xu, C.,Viola, R.E.
Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue.
Biochemistry, 47:3484-3492, 2008
Cited by
PubMed: 18293939
DOI: 10.1021/bi702400x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon