2O3Z
X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate
Summary for 2O3Z
Entry DOI | 10.2210/pdb2o3z/pdb |
Related | 1P42 |
Descriptor | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, SULFATE ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | lipid a biosynthesis, lipid synthesis, lpxc, 3-heptyloxybenzoate, hydrolase |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 2 |
Total formula weight | 63006.26 |
Authors | Gennadios, H.A.,Whittington, D.A.,Christianson, D.W. (deposition date: 2006-12-02, release date: 2007-02-27, Last modification date: 2023-08-30) |
Primary citation | Shin, H.,Gennadios, H.A.,Whittington, D.A.,Christianson, D.W. Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC. Bioorg.Med.Chem., 15:2617-2623, 2007 Cited by PubMed: 17296300DOI: 10.1016/j.bmc.2007.01.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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