2O3M

Monomeric G-DNA tetraplex from human C-kit promoter

Summary for 2O3M

• Entry DOI: 10.2210/pdb2o3m/pdb
• Related: 2A5P
• Descriptor: 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3' (1 entity in total)
• Functional Keywords: g-tetrad;parallel g-quadruplex; edgewise, single-residue cha reversal, 5-nucleotide snap-back loops;broken strand topolog, dna
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 7028.52

Authors

Phan, A.T.,Kuryavyi, V.V.,Burge, S.,Neidle, S.,Patel, D.J. (deposition date: 2006-12-01, release date: 2007-05-22, Last modification date: 2023-12-27)

• Primary citation: Phan, A.T.,Kuryavyi, V.V.,Burge, S.,Neidle, S.,Patel, D.J.; Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.; J.Am.Chem.Soc., 129:4386-4392, 2007; PubMed: 17362008; DOI: 10.1021/ja068739h

Experimental method

SOLUTION NMR