2O36
Crystal structure of engineered thimet oligopeptidase with neurolysin specificity in neurotensin cleavage site
Summary for 2O36
| Entry DOI | 10.2210/pdb2o36/pdb |
| Related | 1I1I 1S4B |
| Descriptor | Thimet oligopeptidase, ZINC ION (3 entities in total) |
| Functional Keywords | thermolysin-like domain, substrate-binding channel, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P52888 |
| Total number of polymer chains | 1 |
| Total formula weight | 77547.36 |
| Authors | Rodgers, D.W.,Lim, E.J. (deposition date: 2006-11-30, release date: 2007-01-23, Last modification date: 2023-08-30) |
| Primary citation | Lim, E.J.,Sampath, S.,Coll-Rodriguez, J.,Schmidt, J.,Ray, K.,Rodgers, D.W. Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase. J.Biol.Chem., 282:9722-9732, 2007 Cited by PubMed: 17251185DOI: 10.1074/jbc.M609897200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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