2O2V
Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox)
Summary for 2O2V
Entry DOI | 10.2210/pdb2o2v/pdb |
Descriptor | Dual specificity mitogen-activated protein kinase kinase 5, Mitogen-activated protein kinase kinase kinase 3 (3 entities in total) |
Functional Keywords | mitogen activated protein kinase kinase 5, map2k5, mek5, mkk5, prkmk5, map kinase 5, phox, phox-domain, mitogen activated protein kinase kinase kinase 3, mekk3, mapkkk3, map/erk kinase kinase 3, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 22426.39 |
Authors | Filippakopoulos, P.,Savitsky, P.,Ugochukwu, E.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-11-30, release date: 2006-12-12, Last modification date: 2023-08-30) |
Primary citation | Filippakopoulos, P.,Savitsky, P.,Ugochukwu, E.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S. Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox) To be Published, |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
Download full validation report