2NZT

Crystal structure of human hexokinase II

Summary for 2NZT

• Entry DOI: 10.2210/pdb2nzt/pdb
• Descriptor: Hexokinase-2, alpha-D-glucopyranose, 6-O-phosphono-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: glucose, glucose-6-phosphate, non-protein kinase, hexokinase, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 202990.75

Authors

Rabeh, W.M.,Zhu, H.,Nedyalkova, L.,Tempel, W.,Wasney, G.,Landry, R.,Vedadi, M.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2006-11-25, release date: 2006-12-05, Last modification date: 2023-08-30)

• Primary citation: Nawaz, M.H.,Ferreira, J.C.,Nedyalkova, L.,Zhu, H.,Carrasco-Lopez, C.,Kirmizialtin, S.,Rabeh, W.M.; The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation.; Biosci.Rep., 38:-, 2018; PubMed: 29298880; DOI: 10.1042/BSR20171666

Experimental method

X-RAY DIFFRACTION (2.45 Å)