2NZT

Crystal structure of human hexokinase II

2NZT の概要

• エントリーDOI: 10.2210/pdb2nzt/pdb
• 分子名称: Hexokinase-2, alpha-D-glucopyranose, 6-O-phosphono-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: glucose, glucose-6-phosphate, non-protein kinase, hexokinase, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 202990.75

構造登録者

Rabeh, W.M.,Zhu, H.,Nedyalkova, L.,Tempel, W.,Wasney, G.,Landry, R.,Vedadi, M.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2006-11-25, 公開日: 2006-12-05, 最終更新日: 2023-08-30)

• 主引用文献: Nawaz, M.H.,Ferreira, J.C.,Nedyalkova, L.,Zhu, H.,Carrasco-Lopez, C.,Kirmizialtin, S.,Rabeh, W.M.; The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation.; Biosci.Rep., 38:-, 2018; PubMed: 29298880; DOI: 10.1042/BSR20171666

実験手法

X-RAY DIFFRACTION (2.45 Å)