2NSH

E. coli PurE H45Q mutant complexed with nitro-AIR

Summary for 2NSH

• Entry DOI: 10.2210/pdb2nsh/pdb
• Related: 2ATE 2NSJ 2NSL
• Descriptor: Phosphoribosylaminoimidazole carboxylase catalytic subunit, ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE (3 entities in total)
• Functional Keywords: central three-layer alpha-beta-alpha sandwich, kinked c-terminal helix, lyase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 18129.44

Authors

Ealick, S.E.,Morar, M. (deposition date: 2006-11-04, release date: 2007-04-24, Last modification date: 2023-12-27)

• Primary citation: Hoskins, A.A.,Morar, M.,Kappock, T.J.,Mathews, I.I.,Zaugg, J.B.,Barder, T.E.,Peng, P.,Okamoto, A.,Ealick, S.E.,Stubbe, J.; N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.; Biochemistry, 46:2842-2855, 2007; PubMed: 17298082; DOI: 10.1021/bi602436g

Experimental method

X-RAY DIFFRACTION (1.8 Å)