2NPT

Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)

Summary for 2NPT

• Entry DOI: 10.2210/pdb2npt/pdb
• Descriptor: Dual specificity mitogen-activated protein kinase kinase 5, Mitogen-activated protein kinase kinase kinase 2 (3 entities in total)
• Functional Keywords: mitogen activated protein kinase kinase 5, map2k5, mek5, mkk5, prkmk5, map kinase kinase 5, phox, phox-domain, mitogen activated protein kinase kinase kinase 2, map3k2, mapk/erk kinase kinase 2, mapkkk2, mek kinase 2, mekk2, mekk2b, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q9Y2U5
• Total number of polymer chains: 4
• Total formula weight: 46953.85

Authors

Filippakopoulos, P.,Debreczeni, J.,Papagrigoriou, V.,Turnbull, A.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-10-30, release date: 2006-11-28, Last modification date: 2023-08-30)

• Primary citation: Filippakopoulos, P.,Debreczeni, J.,Papagrigoriou, V.,Turnbull, A.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.; Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox); To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)