2NPT

Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)

2NPT の概要

• エントリーDOI: 10.2210/pdb2npt/pdb
• 分子名称: Dual specificity mitogen-activated protein kinase kinase 5, Mitogen-activated protein kinase kinase kinase 2 (3 entities in total)
• 機能のキーワード: mitogen activated protein kinase kinase 5, map2k5, mek5, mkk5, prkmk5, map kinase kinase 5, phox, phox-domain, mitogen activated protein kinase kinase kinase 2, map3k2, mapk/erk kinase kinase 2, mapkkk2, mek kinase 2, mekk2, mekk2b, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q9Y2U5
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 46953.85

構造登録者

Filippakopoulos, P.,Debreczeni, J.,Papagrigoriou, V.,Turnbull, A.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2006-10-30, 公開日: 2006-11-28, 最終更新日: 2023-08-30)

• 主引用文献: Filippakopoulos, P.,Debreczeni, J.,Papagrigoriou, V.,Turnbull, A.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.; Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox); To be Published,

実験手法

X-RAY DIFFRACTION (1.75 Å)