2NOV

Breakage-reunion domain of S.pneumoniae topo IV: crystal structure of a gram-positive quinolone target

Summary for 2NOV

Entry DOI	10.2210/pdb2nov/pdb
Descriptor	DNA topoisomerase 4 subunit A (2 entities in total)
Functional Keywords	protein, parc, topo iv, gram-positive bacteria, quinolone target, dna binding, dna cleavage, isomerase
Biological source	Streptococcus pneumoniae
Cellular location	Cell membrane ; Peripheral membrane protein : P72525
Total number of polymer chains	4
Total formula weight	225821.74
Authors	Laponogov, I.,Veselkov, D.A.,Sohi, M.K.,Pan, X.S.,Achari, A.,Yang, C.,Ferrara, J.D.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2006-10-26, release date: 2006-11-14, Last modification date: 2023-08-30)
Primary citation	Laponogov, I.,Veselkov, D.A.,Sohi, M.K.,Pan, X.S.,Achari, A.,Yang, C.,Ferrara, J.D.,Fisher, L.M.,Sanderson, M.R. Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target. PLoS ONE, 2:e301-e301, 2007 Cited by PubMed: 17375187 DOI: 10.1371/journal.pone.0000301 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.67 Å)

Structure validation