2NOI
Structure of G42A human 8-oxoguanine glycosylase crosslinked to undamaged G-containing DNA
Summary for 2NOI
Entry DOI | 10.2210/pdb2noi/pdb |
Related | 1EBM 1YQK 1YQR 2NOB 2NOE 2NOF 2NOH 2NOL 2NOZ |
Descriptor | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*C*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', N-glycosylase/DNA lyase, ... (5 entities in total) |
Functional Keywords | n-glycosylase/dna lyase, dna repair, 8-oxoguanine, hydrolase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm . Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 3 |
Total formula weight | 45764.39 |
Authors | Radom, C.T.,Banerjee, A.,Verdine, G.L. (deposition date: 2006-10-25, release date: 2006-11-21, Last modification date: 2023-12-27) |
Primary citation | Radom, C.T.,Banerjee, A.,Verdine, G.L. Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282:9182-9194, 2007 Cited by PubMed: 17114185DOI: 10.1074/jbc.M608989200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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