2NNQ
Crystal structure of human adipocyte fatty acid binding protein in complex with ((2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-3-biphenylyl)oxy)acetic acid
Summary for 2NNQ
Entry DOI | 10.2210/pdb2nnq/pdb |
Descriptor | Fatty acid-binding protein, adipocyte, SULFATE ION, ((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPHENYLYL)OXY)ACETIC ACID, ... (4 entities in total) |
Functional Keywords | transport, lipid-binding, lipid transport |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15090 |
Total number of polymer chains | 1 |
Total formula weight | 15275.38 |
Authors | Jacobson, B.L. (deposition date: 2006-10-24, release date: 2007-06-12, Last modification date: 2024-04-03) |
Primary citation | Sulsky, R.,Magnin, D.R.,Huang, Y.,Simpkins, L.,Taunk, P.,Patel, M.,Zhu, Y.,Stouch, T.R.,Bassolino-Klimas, D.,Parker, R.,Harrity, T.,Stoffel, R.,Taylor, D.S.,Lavoie, T.B.,Kish, K.,Jacobson, B.L.,Sheriff, S.,Adam, L.P.,Ewing, W.R.,Robl, J.A. Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg.Med.Chem.Lett., 17:3511-3515, 2007 Cited by PubMed: 17502136DOI: 10.1016/j.bmcl.2006.12.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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