2NNA
Structure of the MHC class II molecule HLA-DQ8 bound with a deamidated gluten peptide
Summary for 2NNA
Entry DOI | 10.2210/pdb2nna/pdb |
Descriptor | MHC class II antigen, gluten peptide, ... (4 entities in total) |
Functional Keywords | major histocompatibility complex hla-dq8, deamidated gluten peptide, post translational modification, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 46835.02 |
Authors | Henderson, K.N.,Tye-Din, J.A.,Rossjohn, J.,Anderson, R.P. (deposition date: 2006-10-24, release date: 2007-09-04, Last modification date: 2023-10-25) |
Primary citation | Henderson, K.N.,Tye-Din, J.A.,Reid, H.H.,Chen, Z.,Borg, N.A.,Beissbarth, T.,Tatham, A.,Mannering, S.I.,Purcell, A.W.,Dudek, N.L.,van Heel, D.A.,McCluskey, J.,Rossjohn, J.,Anderson, R.P. A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease Immunity, 27:23-34, 2007 Cited by PubMed: 17629515DOI: 10.1016/j.immuni.2007.05.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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