2NNA

Structure of the MHC class II molecule HLA-DQ8 bound with a deamidated gluten peptide

2NNA の概要

• エントリーDOI: 10.2210/pdb2nna/pdb
• 分子名称: MHC class II antigen, gluten peptide, ... (4 entities in total)
• 機能のキーワード: major histocompatibility complex hla-dq8, deamidated gluten peptide, post translational modification, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 46835.02

構造登録者

Henderson, K.N.,Tye-Din, J.A.,Rossjohn, J.,Anderson, R.P. (登録日: 2006-10-24, 公開日: 2007-09-04, 最終更新日: 2023-10-25)

• 主引用文献: Henderson, K.N.,Tye-Din, J.A.,Reid, H.H.,Chen, Z.,Borg, N.A.,Beissbarth, T.,Tatham, A.,Mannering, S.I.,Purcell, A.W.,Dudek, N.L.,van Heel, D.A.,McCluskey, J.,Rossjohn, J.,Anderson, R.P.; A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease; Immunity, 27:23-34, 2007; PubMed: 17629515; DOI: 10.1016/j.immuni.2007.05.015

実験手法

X-RAY DIFFRACTION (2.1 Å)