2NGR

TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.

2NGR の概要

• エントリーDOI: 10.2210/pdb2ngr/pdb
• 分子名称: PROTEIN (GTP BINDING PROTEIN (G25K)), PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)), MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: transition state, g-protein, gap, cdc42, alf3., hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P60953; Cytoplasm: Q07960
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48286.35

構造登録者

Nassar, N.,Hoffman, G.,Clardy, J.,Cerione, R. (登録日: 1998-07-31, 公開日: 1999-01-06, 最終更新日: 2023-08-30)

• 主引用文献: Nassar, N.,Hoffman, G.R.,Manor, D.,Clardy, J.C.,Cerione, R.A.; Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.; Nat.Struct.Biol., 5:1047-1052, 1998; PubMed: 9846874; DOI: 10.1038/4156

実験手法

X-RAY DIFFRACTION (1.9 Å)