2N99

Solution structure of the SLURP-2, a secreted isoform of Lynx1

Summary for 2N99

• Entry DOI: 10.2210/pdb2n99/pdb
• NMR Information: BMRB: 25887
• Descriptor: Ly-6/neurotoxin-like protein 1 (1 entity in total)
• Functional Keywords: neuromodulator, cell proliferation, three-finger protein, nicotinic acetylcholine receptor, muscarinic acetylcholine receptor, epithelium, keratinocyte, neuropeptide
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Secreted . Isoform 2: Cell membrane ; Lipid-anchor, GPI-anchor . Isoform 3: Secreted: Q9BZG9
• Total number of polymer chains: 1
• Total formula weight: 8163.42

Authors

Paramonov, A.S.,Shenkarev, Z.O.,Lyukmanova, E.N.,Arseniev, A.S. (deposition date: 2015-11-11, release date: 2016-09-21, Last modification date: 2023-06-14)

• Primary citation: Lyukmanova, E.N.,Shulepko, M.A.,Shenkarev, Z.O.,Bychkov, M.L.,Paramonov, A.S.,Chugunov, A.O.,Kulbatskii, D.S.,Arvaniti, M.,Dolejsi, E.,Schaer, T.,Arseniev, A.S.,Efremov, R.G.,Thomsen, M.S.,Dolezal, V.,Bertrand, D.,Dolgikh, D.A.,Kirpichnikov, M.P.; Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors.; Sci Rep, 6:30698-30698, 2016; PubMed: 27485575; DOI: 10.1038/srep30698

Experimental method

SOLUTION NMR