2N3O
Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA
Summary for 2N3O
| Entry DOI | 10.2210/pdb2n3o/pdb |
| Related | 1SJQ 2AD9 |
| NMR Information | BMRB: 25652 |
| Descriptor | Polypyrimidine tract-binding protein 1, RNA (5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3') (2 entities in total) |
| Functional Keywords | polypyirimine tract binding protein, ires, ptb, c-terminal helix formation, rna binding protein-rna complex, rna binding protein/rna |
| Biological source | Homo sapiens (human) More |
| Cellular location | Nucleus: P26599 |
| Total number of polymer chains | 2 |
| Total formula weight | 20683.51 |
| Authors | Maris, C.,Jayne, S.F.,Damberger, F.F.,Ravindranathan, S.,Allain, F.H.-T. (deposition date: 2015-06-08, release date: 2016-08-10) |
| Primary citation | Maris, C.,Jayne, S.F.,Damberger, F.F.,Ravindranathan, S.,Allain, F.H.-T. C-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity. To be Published, |
| Experimental method | SOLUTION NMR |
Structure validation
Download full validation report
