2N2C
NMR Structure of TDP-43 prion-like hydrophobic helix in DPC
Summary for 2N2C
Entry DOI | 10.2210/pdb2n2c/pdb |
NMR Information | BMRB: 25595 |
Descriptor | TAR DNA-binding protein 43 (1 entity in total) |
Functional Keywords | als, prion-like domain, hydrophobic helices, membrane interaction, dpc, tar dna-binding protein-43, dna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q13148 |
Total number of polymer chains | 1 |
Total formula weight | 4336.97 |
Authors | |
Primary citation | Lim, L.,Song, J. ALS-causing mutations significantly perturb the self-assembly and interaction with nucleic acid of the intrinsically-disordered prion-like domain of TDP-43 To be Published, |
Experimental method | SOLUTION NMR |
Structure validation
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